Drug interactions may perhaps improve how your prescription drugs operate or enhance your risk for serious Negative effects. This doc would not incorporate all attainable drug interactions.
When utilized for an prolonged time, this medication may well not function too and should call for distinct dosing. Discuss with your medical professional if this medication stops Performing very well.
Don't forget, hold this and all other medicines out in the get to of children, hardly ever share your medicines with Other folks, and use this medication only for the sign prescribed.
Stay away from the usage of Promethazine with Codeine Oral Answer in clients with head harm, intracranial lesions, or simply a pre-existing increase in intracranial stress. In sufferers who can be prone to the intracranial effects of CO two retention (eg., those with proof of amplified intracranial force or brain tumors), Promethazine with Codeine Oral Resolution might lower respiratory drive, and the resultant CO 2 retention can even more maximize intracranial strain.
Therapy of overdosage is pushed by the general scientific presentation, and contains discontinuation of Promethazine with Codeine Oral Remedy with each other with establishment of acceptable therapy. Give Key awareness to the reestablishment of sufficient respiratory exchange through provision of the patent and guarded airway as well as institution of assisted or controlled air flow.
No proof of tumorigenicity was observed in male and woman mice at codeine dietary doses approximately 400 mg/kg/working day (around equivalent to forty four occasions the MRHD with a mg/m 2 foundation). Codeine wasn't mutagenic while in the in vitro bacterial reverse mutation assay or clastogenic within the in vitro Chinese hamster ovary (CHO) mobile chromosomal aberration assay. Fertility research with codeine haven't been conducted.
This medication may well contain sugar and/or Liquor. Warning is encouraged if you have diabetic issues, Alcoholic beverages dependence, or liver condition. Inquire your physician or pharmacist about applying this products safely and securely.
Promethazine with Codeine Oral Option ought to be employed with warning in people with significant impairment of renal function, and sufferers should be monitored intently for respiratory despair, sedation, and hypotension.
Shop at area temperature. Protect from light-weight. Retailer inside of a dry place. Never retailer in a toilet. Continue to keep all medicine in a secure place. Preserve all medicine out of your attain of children and pets. Throw absent unused or expired drugs.
Promethazine VC with Codeine can slow or end your breathing, and death may perhaps arise. Somebody caring for you'll want to seek emergency medical notice if you have sluggish breathing with extensive pauses, blue coloured lips, or If you're hard to get up.
Drug interactions might transform how your medications get the job done or improve your possibility for serious Uncomfortable side effects. This doc doesn't consist of all possible drug interactions.
DailyMed will supply this notification to the desktop, World wide web browser, or e-mail dependant upon the RSS Reader you select to make use of. To look at up-to-date drug label back links, paste the RSS feed handle (URL) shown below into a RSS reader, or use a browser which supports RSS feeds, such as Safari for Mac OS X.
Advise clients to usually use an correct milliliter measuring machine when measuring and administering Promethazine with Codeine Oral Solution. Inform sufferers that family teaspoon is not an precise measuring product and these kinds of use may lead to overdosage and really serious adverse reactions [see Overdosage ( 10) ]. For prescriptions the place a measuring unit is not really presented, a pharmacist can offer an ideal calibrated measuring unit and can provide Recommendations for measuring the correct dose. five.eight Things to do Requiring Psychological Alertness: Risks of
The concomitant utilization of anticholinergic medication with Promethazine with Codeine Oral Solution may possibly boost risk of urinary retention and/or critical constipation, which may result in paralytic ileus [see Warnings read more and Safeguards ( 5.eleven) ]. Check people for signs of urinary retention or lessened gastric motility when Promethazine with Codeine Oral Option is utilized concomitantly with anticholinergic prescription drugs.